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Shruthi, B.
- Fast Dissolving Drug Delivery System - a Review
Authors
1 Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, IN
Source
Research Journal of Pharmacy and Technology, Vol 6, No 1 (2013), Pagination: 4-11Abstract
It is very well known that a drug can be administered through many different routes so as to produce a systemic pharmacological effect.
The main route of administrating a drug administration is the oral route which is the oldest and most commonly used because of its ease of administration, self-medication and avoidance of pain as compared to parental route. Despite of the tremendous advancement in oral route some of the people find difficultly in swallowing tablet and other oral dosage form, so in order to troubleshoot all these problem associated with oral route, fast dissolving drug delivery systems (FDDS) were first came into existence in 1970 as an alternative to tablets, syrups and capsules, for pediatric and geriatric patients which rapidly disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over conventional dosage form.
The fast dissolving tablets are prepared by freeze-drying, tablet molding, spray drying, sublimation, direct compression, cotton candy process, mass-extrusion, nanonization, methods.
Formulation of oral films involves the application of both aesthetic and performance characteristics such as plasticised hydrocolloids, active pharmaceutical ingredient, taste masking agent being laminated by solvent casting or hot melt extrusion.
This review describes about the formulation methodology, evaluation parameters of fast dissolving dosage forms
Keywords
Fast Dissolving Drug Delivery System, Fast Dissolving Tablets, Fast Dissolving Films, Methods of Preparation, Evaluation ParametersReferences
- Pfister W, Ghosh T, Intraoral delivery systems: An overview, current status and future trends. In Tapash Ghosh, William Pfister (Ed.), Drug Delivery to the Oral Cavity: Molecules to Market (pp.1-34). Florida: CRC Press, Taylor and Francis gp, 2005.
- Shimoda H, Taniguchi K, Nishimura M, Tsukioka K MT, Yamashita H, Inagaki N, Hirano K, Yamamot M, Kinosada Y , Itoh Y. Preparation of a fast dissolving oral thin film containing dexamethasone: A possible application to antiemesis during cancer chemotherapy. European Journal of Pharmaceutics and Biopharmaceutics, 2009; 73(3): 361-365.
- Arunachalam A, Karthikeyan M, Kumar S A, Konam K, Prasad P H, Sethuraman S, Manidipa S. Fast Dissolving Drug Delivery System: A Review. Journal of Global Trends in Pharmaceutical Sciences. 2010; 1(1): 92-110.
- Garg S, Goldman D, Krumme M, Rohan L C, Smoot S, Friend D R. Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. Antiviral Research. 2010; 88: S19-S29.
- Saini S, Nanda A, Hooda M, Komal. Fast dissolving films (FDF): innovative drug delivery system. Pharmacologyonline. 2011; 2: 919-928.
- Arun A, Amrish C. Fast Drug Delivery Systems: A Review. Der Pharmacia Lettre, 2010; 2(2): 350-361.
- Chandan S, Varun D, Ashish G, Dabeer A, Ayaj A.Orally disintegrating tablets: A review. International Journal Of Pharmacy and Life Science. 2010; 1(5):250-256.
- Advances in Formulation of Orally Disintegrating Dosage Forms: A Review Article by Rakesh Kumar Bhasin, Nirika Bhasin, Pradip Kumar Ghosh Dobetti L: Fast-Melting Tablets: Developments and Technologies. Pharm. Technol., Drug delivery supplement, 44-50, 2001.
- Masaki K: Intra Buccally Disintegrating Preparation and Production Thereof. US patent 5,466,464, 1995.
- Indurwade N.H, Rajyaguru T.H, Nakhat P.D: Novel Approach – Fast Dissolving Tablets. Indian Drugs, 39(8), 2002.
- Allen L.V, Wang B: Method of making a rapidly dissolving tablet. US Patent No. 5,635,210, 1997.
- Allen L.V, Wang B: Rapidly Dissolving Tablets. US Patent No. 5,807,576, 1998.
- Allen L.V, Wang B: Process for making a particulate support matrix for making rapidly dissolving tablets. US Patent No. 5,587,180, 1996.
- Allen L.V, Wang B: Particulate support matrix for making rapidly dissolving tablets. US Patent No.5,595,761, 1997.
- Heinemann H, Rothe W: Preparation of porous tablets. US Patent No. 3,885,026, 1975.
- Knitsch K.W: Production of porous tablets. US Patent No. 4,134,943, 1979.
- Roser B.J, Blair J: Rapidly soluble oral dosage forms, Methods of making same, and Compositions thereof. US Patent No. 5,762,961, 1998.
- Koizumi K.I.: New method of preparing high porosity rapidly saliva soluble compressed tablets using mannitol with camphor, a subliming material. Int. J. Pharm., 152:127-131, 1997.
- Gohel M.C, Patel M.M, Amin A.F, Agrawal R, Dave R, Bariya N.: Formulation design and optimization of mouth dissolving tablets of Nimesulide using Vacuum drying technique. AAPS Pharm. Sci. Tech., 5 (3): Article 36, 2004.
- Makino T, Yamada M, Kikuta J.I: Fast dissolving tablet and its production. US Patent No. 5,720,974, 1998.
- Fuisz et al, Easily processed tablet compositions, United States Patent 6,277,406 (Issued 21 August 2001).
- Fuisz et al, Process and apparatus for producing shear form matrix material United States Patent 6,171,607 (Issued 9 January 2001).
- Mezaache et al, Dosage form containing taste masked active agents United States Patent 6,165,512 (Issued 26 December 2000).
- Bhaskaran, S., Narmada, G.V, Indian Pharmacist, 1(2), 9-12, 2002.
- Mandel; Frederick S. et al, Orthopedic mixtures prepared by Supercritical fluid processing techniques, United States Patent 6,579,532 (Issued17 July 2003).
- Lalla. J K., Mamania, H. M., Fast dissolving rofecoxib tablets, Indian J. Pharm. Sci., 2004, 59(4), 23-26.
- Kuchekar, B. S., Mahajan, S., and Bandhan, A. C., Mouth dissolve tablets of sumatriptan, Indian Drugs, 2004,41(10), 592- 598.
- Lorenzp- Lamosa, M.L., Cuna, M., Vila-Jato, J.L. and Torres, D., J. Microencapsul., 1997, 14, 607.
- Shirai, Y., Sogo, K., Yamamoto, K., Kojima, K., Fujioka, H., Makita, H. and Nakamura,Y., Biol. Pharm. Bull, 1993, 16, 172.
- Shirai, Y., Sogo, K., Fujioka, H. and Nakamura, Y., Biol. Pharm. Bull., 17, 1994, 427. Profile Resources at Business. Com. Cima Labs - Profile. 27 May 2001.
- Makino, T., Yamada, M. and Kikuta, J., Fast dissolving tablet and its production, 1993, European Patent, http://www.business. com/ directory/ pharmaceuticals and biotech nology /drug.
- Shukla D, Chakraborty S, Singh S, Mishra B . Mouth Dissolving Tablets I: An Overview of Formulation Technology. Sci Pharm., 2009; 76: 309–326.
- Fast dissolving films: a novel approach to oral drug delivery by Aggarwal Jyoti, Singh Gurpreet ,Saini Seema Technical Brief 2010. Vol 3 Particle Sciences Drug Development Services.
- Coppens, K.A., M.J. Hall, S.A. Mitchell and M.D. Read, 2005. Hypromellose, Ethyl cellulose and Polyethylene oxide used in hot melt extrusion. Pharmaceutical Technol., pp: 1-6.
- Frey, 2006. Film Strips and Pharmaceuticals. Pharmaceutical Manufacturing and Packaging Source, pp: 92-93.
- Orally fast dissolving films as dominant dosage form for quick release by Dipika Parmar ,Dr. Upender Patel, Bhavin Bhimani, Aditi Tripathi, Dhiren Daslaniya , Ghanshyam Patel
- Drug Delivery through Osmotic Micropump - a Review
Authors
1 Centre for Pharmaceutical Sciences, IST, JNTU, Kukatpally, Hyderabad, IN
Source
Research Journal of Pharmacy and Technology, Vol 6, No 1 (2013), Pagination: 12-16Abstract
This review article discusses the drug delivery systems using osmotic principles for pumping and some of the milestones in Osmotic Drug Delivery (ODDs) systems developed till date. Recent technological advances led to the development of low flow rate biocompatible micropumps. Drug delivery methods are considered as one of the salient characteristic feature to enhance efficacy of a drug. Micropumps help in achieving this by controlled drug delivery which is not possible in traditional methods (tablets and injections). Osmotic systems further increases the patient compliance, decreases dose related adverse events and most importantly helps in controlling or constant drug release (zero-order). Drug release from these systems is independent of pH and other physiological parameters to a large extent. Based on the potential advantages and persistent market demand for new technological advances in controlling the drug delivery rate, it is evident that osmotic pumps have bright scope in drug development.Keywords
Osmotic Pump, Drug Delivery, Zero-orderReferences
- Verma RK, et al., Osmotically controlled oral drug delivery, Drug Dev. Ind. Pharm. 26; 2000: 695–708.
- Verma RK, et al., Osmotic pumps in drug delivery, Crit. Rev. Ther. Drug Carrier Syst. 21; 2004: 477–520.
- Malaterre V, et al., Oral osmotically driven systems: 30 years of development and clinical use, Eur. J. Pharm. Biopharm. 73; 2009: 311–323.
- Gupta BP et al., Osmotically controlled drug delivery system with associated drugs, J. Pharm. Pharm. Sci. 13; 2010: 571–588.
- Babu CA, et al., Controlled-porosity osmotic pump tablets—an overview, J. Pharm. Res. Health Care 2; 2010: 114–126.
- Gosh T, Gosh A, Drug delivery through osmotic systems — an overview, J. Appl. Pharm. Sci. 1; 2011: 38–49.
- Baker R, Osmotic and mechanical devices, In: Controlled release of biologically active agents, New York, John Wiley, 1987.
- Martin A, Solution of non-electrolytes, In: Physical pharmacy 4 ed. New Delhi, BI Waverly. 1993.
- Rose S, Nelson JF, A continuous long term injector, Australian J Exp Biol. 33; 1955: 415-420.
- Jerzewski RJ, Chien YW, Osmotic drug delivery, In: Kydonieus A ed. Treatise on controlled drug delivery, New York, Marcel Dekker. 1992.
- Santus G, Waker RW, Osmotic Drug delivery: A review of the patient literature, J Control Release, 35; 1995: 1-21.
- Higuchi T, Leeper HM. ALZA corp assignee. Osmotic dispenser, US patent 3,732,865. May 15, 1973.
- Cortese R, Theeuwes F. ALZA corp assignee. Osmotic device with hydrogel driving member, US patent 4,327,725. May 4, 1982.
- Zentner GM, et al., The controlled porosity osmotic pump, J control release, 1; 1985: 269-282.
- Zentner GM, et al., Osmotic flow through controlled porosity films: an approach to delivery of water soluble compounds, J control release, 2; 1985: 217-229.
- Eckenhoff B, et al., ALZA Corp., assignee. Delivery system controlled administration of beneficial agent to ruminants. US Patent 4,595,583. Jun. 17, 1986.
- Urquhart J. Controlled drug delivery: therapeutic and pharmacological aspects. J Int Med 248; 2000:357-376.
- Urquhart J. Can drug delivery systems deliver value in the new pharmaceutical marketplace? Br J Clin Pharmacol 1997: 44413- 419.
- Wong P, et al., ALZA Corp., assignee. Osmotic dosage system for liquid drug delivery US Patent 5,413,572. May 9,1995.
- Dong L, et al., ALZA Corp., assignee. Dosage form comprising liquid formulation. US Patent 6,174,547. Jan. 16, 2001.
- Scholz OA, et al., Drug delivery from the oral cavity: focus on a novel mechatronic delivery device, Drug Discov. Today 13; 2008: 247–253.
- Goettsche T, et al., Highly integrated oral drug delivery system with valve based on electro-active-polymer, Proc. Of MEMS2007, Kobe, 2007: pp. 461–464.
- Goettsche T, Haeberle S, Integrated oral drug delivery system with valve based on polypyrrole, in: F. Carpi, E. Smela (Eds.), Biomedical Applications of Electroactive Polymer Actuators, JohnWiley & Sons, Ltd., Chichester, 2009: pp. 301–316.
- Velten T, et al., Biocompatible flow sensor with integrated solvent concentration measurement, Sens. Actuators, A 145; 2008; 257–262.
- Giannola LI, et al., New prospectives in the delivery of galantamine for elderly patients using the IntelliDrug intraoral device: in vivo animal studies, Curr. Pharm. Des. 16; 2010: 653– 659.
- Moscicka AE, et al., IntelliDrug implant for medicine delivery in Alzheimer's disease treatment, Macromol. Symp. 253 (2007) 134–138.
- Ciach T, Intraoral implant for drug delivery in addiction and chronic disease treatment, Inz. Chem. Procesowa 28; 2007: 559– 565.
- Campisi G, et al., Bioavailability in vivo of naltrexone following transbuccal administration by an electronically-controlled intraoral device: a trial on pigs, J. Control. Release 145; 2010: 214–220.
- Schumacher A., et al., Intraoral drug delivery microsystem, in: J. Vander Sloten, P. Verdonck, M. Nyssen, J. Haueisen (Eds.), ECIFMBE 2008, IFMBE Proceedings, 22, Springer, Berlin Heidelberg, 2008, pp. 2352–2355.